Managing cortisol levels and balancing the HPA axis are key for establishing a healthy stress response.* The hypothalamic-pituitary-adrenal (HPA) axis helps maintain hormonal homeostasis during times of stress. Cortisol is produced by the adrenal cortex and plays an important role in regulating energy metabolism, heart rate, appetite, and immune function. Because of its central role as a key stress hormone, cortisol is often thought of as a bridge between stress and its health impact. Typically, cortisol follows a circadian rhythm, peaking in the morning with a gradual decline throughout the day. However, during times of stress, cortisol is continuously produced and can impact whole-body wellness. Our best-selling Cortisol Manager contains proprietary blends of Sensoril brand ashwagandha extract and L-theanine and of Magnolia and epimedium extracts, as well as phosphatidylserine, and is designed to: Balance cortisol levels* Help reduce stress* Promote relaxation to support restful sleep* Integrative Therapeutics' HPA Adapt combines key adaptogenic herbs to help the body manage both mental and physical stress.*