I am on day 4, I was not sure if I would have to build up to this working but from day one I could feel it's effects. A nice boost of energy and overall feel of good mood. I feel more driven as well. By the end of the night I am tired tired, which is not a bad thing, it means I don't need to take something else in order to fall asleep. I fall asleep laying on my back and wake up that way too. Meaning no tossing and turning. I now have this on auto ship, I just wish it came in a bigger quantity bottle. For me the measurements on the dropper is no problem, I'm not sure how to make this more visually impaired friendly, however I have found that one squeeze brings it right to the dosage. And I actually love the taste. Kinda chocolate mint..Update: realized around day 6 that I no longer had the achiness I once felt after sitting for a few hours working nor is my ever constant left Achilles heel sore. Things are going so good that I'm wondering if it's placebo effect, however I'd take that too. Simply love this product.Update 9/7/24I have continued taking this daily each morning and it works just the same as before. I have since added the tumeric drops from this brand in hopes of helping arthritis in 2 fingers and the ashwaganda drops from this brand at night for perimenopause support with sleep as well as milk thistle for liver support which I hear is what is needed for thyroid issues, in March I had my TSH tested for the first time and was in the 6s showing as hypothyroidism, on 8/26 I finally followed up and did a fuller thyroid panel and my TSH was cut in half and back within a normal range, my t3 was just below the low range... All in all in the last two weeks I have gotten off of my 7+ year prescription anti anxiety and anti depressant medicine.